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[Method for evaluating the neuraminidase activity of receptordestroying enzyme (RDE) compounds using the influenza virus.]

A Y FedorovO P Zhirnov
Published in: Voprosy virusologii (2021)
The designed method allows the accurate measurement of the receptor-destroying (neuraminidase) activity of RDE compounds and the comparison of the compounds with each other. This test is necessary to optimize the RTGA protocol when monitoring blood sera of animals and humans after influenza infection and/or Acute Respiratory diseases (ARD). The designed method can be included in the guidelines of regulations for the RTGA protocol, which is used in different laboratories to monitor the epidemic process of influenza and ARD infections.
Keyphrases
  • randomized controlled trial
  • liver failure
  • high resolution
  • respiratory failure
  • mass spectrometry
  • clinical evaluation