Characterization of Primary Cilia Formation in Human ESC-Derived Retinal Organoids.

Ke Ning Ziming LuoTia J KowalMatthew TranRishab MajumderTrent M JarinAlbert Y WuJeffrey L GoldbergYang Sun

Published in: Stem cells international (2023)

Amacrine cells in retinal organoids retain cilia throughout development, whereas RGC ciliation gradually and progressively decreases with organoid maturation.

Keyphrases

induced pluripotent stem cells
optical coherence tomography
diabetic retinopathy
induced apoptosis
endothelial cells
cell cycle arrest
optic nerve
pluripotent stem cells
endoplasmic reticulum stress
cell death
signaling pathway