A novel conserved enhancer at zebrafish zic3 and zic6 loci drives neural expression.

Rashid MinhasAleksandra PaterekMaciej ŁapińskiMichał BazałaVladimir Korzh Cecilia Lanny Winata

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2019)

This transgenic line that expresses green fluorescent protein in the habenula is a valuable resource for studying a specific population of cells in the zebrafish central nervous system. Our observations indicate that a genomic sequence that is conserved between humans and zebrafish acts as an enhancer that likely controls zic3 and zic6 expression.

Keyphrases

binding protein
transcription factor
poor prognosis
induced apoptosis
genome wide
amino acid
long non coding rna
gene expression
oxidative stress
copy number
signaling pathway
living cells
cerebrospinal fluid
protein protein