Effect of an opt-out point-of-care HIV-1 nucleic acid testing intervention to detect acute and prevalent HIV infection in symptomatic adult outpatients and reduce HIV transmission in Kenya: a randomized controlled trial.
Eduard J SandersClara AgutuElise van der ElstAmin HassanEvanson GichuruPeter MugoCarey FarquharJoseph B BabigumiraSteven M GoodreauDeven T HamiltonThumbi Ndung'uMartin SirengoWairimu ChegeSusan M GrahamPublished in: HIV medicine (2021)
Among symptomatic adults aged 18-39 years targeted by our POC NAAT intervention, we identified one chronic HIV infection for every 40 patients and one AHI patient for every 750 patients tested. Although AHI yield was low in this population, routinely offered opt-out testing could diagnose twice as many patients as an approach relying on provider discretion.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- randomized controlled trial
- antiretroviral therapy
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- human immunodeficiency virus
- hepatitis c virus
- intensive care unit
- hiv positive
- nucleic acid
- respiratory failure
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome