Reversions of QuantiFERON-TB Gold Plus in tuberculosis contact investigation: A prospective multicentre cohort study.

Sandra Pérez-RecioMaria D Grijota-CaminoLuis Anibarro-GarcíaRamón Rabuñal-ReyJosefina SabriaPaloma Gijón-VidaurretaVirginia PomarMercedes García-GasallaÁngel Domínguez-CastellanoMatilde TrigoMaría Jesús SantosAlba CebolleroSara RodríguezEsther MogaAnton Penas-TruqueCarmen MartosM Jesús Ruiz-SerranoErika I Garcia-de-CaraFernando AlcaideMiguel Santin

Published in: PloS one (2023)

In this study, TB contact investigations rarely reveal QFT-Plus reversion. These results do not support retesting cases with an initial positive result to reduce the number of preventive treatments.

Keyphrases

mycobacterium tuberculosis
clinical trial
genome wide
pulmonary tuberculosis
study protocol
randomized controlled trial
gene expression
double blind
hepatitis c virus
dna methylation