Intragenic regulation of SOCS3 isoforms.

Oliver KlepschLise Sarah NamerNadine KöhlerRaymond KaempferAnna DittrichFred Schaper

Published in: Cell communication and signaling : CCS (2019)

Both SOCS3 isoforms show a similar potential for inhibiting interleukin-6 signalling but differ in their half-lives. Relative expression of the isoforms depends on intragenic elements yet is independent of PKR signalling.

Keyphrases

poor prognosis
signaling pathway
human health
risk assessment