TRIB3 is highly expressed in the adipose tissue of obese patients and is associated with insulin resistance.

Seul Ki LeeChan Yoon ParkJimin KimDonguk KimHan ChoeJong-Hyeok KimJoon Pio HongYeon Ji LeeYoonseok HeoHye Soon ParkYeon-Jin Jang

Published in: The Journal of clinical endocrinology and metabolism (2021)

Our data indicate that TRIB3 expression in adipose tissue is enhanced in patients with obesity and suggest that the increased TRIB3 dysregulates adipocyte function, which may contribute to the development of insulin resistance.

Keyphrases

insulin resistance
adipose tissue
obese patients
bariatric surgery
high fat diet
high fat diet induced
polycystic ovary syndrome
roux en y gastric bypass
gastric bypass
poor prognosis
metabolic syndrome
skeletal muscle
electronic health record
type diabetes
big data
binding protein
glycemic control
machine learning