Less demand on stem cell marker-positive cancer cells may characterize metastasis of colon cancer.

Takeshi KaidaYoshiki FujiyamaTakafumi SoenoMitsuo YokotaShuji NakamotoTakuya GotoAkiko WatanabeKota OkunoYusuke NieShiori FujinoKazuko YokotaHiroki HaradaYoko TanakaToshimichi TanakaKeigo YokoiKen KojoHirohisa MiuraTakahiro YamanashiTakeo SatoJiichiro SasakiTakafumi SangaiNaoki HikiYusuke KumamotoTakeshi NaitohKeishi Yamashita

Published in: PloS one (2023)

Our transcript expression analysis of cancer stem cell markers did not conclude that their expression could represent aggressive phenotypes of primary and metastatic tumors, and rather represented less demand on stem cell marker-positive cancer cells.

Keyphrases

stem cells
cancer stem cells
poor prognosis
squamous cell carcinoma
small cell lung cancer
cell therapy
rna seq
long non coding rna
single cell
transcription factor