A new acridone with antifungal properties against Candida spp. and dermatophytes, and antibiofilm activity against C. albicans.

D B C de OliveiraL B SilvaB V da SilvaT C BorgesB C MarquesM B Dos SantosL F de OliveiraV S BolzaniA R A RodriguesL O RegasiniAnderson Assunção Andrade

Published in: Journal of applied microbiology (2019)

Because of its in vitro antifungal activity, anti-Candida biofilm effect and moderate cytotoxicity towards normal human cell, M14 may serve as a valuable lead compound to develop a new antifungal agent.

Keyphrases

candida albicans
biofilm formation
endothelial cells
single cell
cell therapy
induced pluripotent stem cells
pluripotent stem cells
high intensity
pseudomonas aeruginosa
staphylococcus aureus
escherichia coli