Attaining sinus rhythm mediates improved outcome with early rhythm control therapy of atrial fibrillation: the EAST-AFNET 4 trial.
Lars EckardtSusanne SehnerAnna SulingKatrin BorofGuenter BreithardtHarry J G M CrijnsAndreas GoetteKarl WegscheiderAntonia ZapfAlan John CammAndreas MetznerPaulus F KirchhofPublished in: European heart journal (2022)
The effectiveness of early rhythm control is mediated by the presence of sinus rhythm at 12 months in the EAST-AFNET 4 trial. Clinicians implementing ERC should aim for rapid and sustained restoration of sinus rhythm in patients with recently diagnosed AF and cardiovascular comorbidities.
Keyphrases
- atrial fibrillation
- heart rate
- catheter ablation
- oral anticoagulants
- left atrial
- left atrial appendage
- direct oral anticoagulants
- study protocol
- clinical trial
- heart failure
- randomized controlled trial
- percutaneous coronary intervention
- phase ii
- phase iii
- systematic review
- palliative care
- stem cells
- coronary artery disease
- quality improvement
- acute coronary syndrome
- mesenchymal stem cells
- open label
- quantum dots
- venous thromboembolism