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Effects of household concrete floors on maternal and child health - the CRADLE trial: a randomised controlled trial protocol.

Mahbubur RahmanFarjana JahanSuhi HanifAfsana YeaminAbul Kasham ShoabJason R AndrewsYing LuSarah BillingtonNils PilotteIreen S ShantaMohammad JubairMustafizur RahmanMamun KabirRashidul HaqueFahmida TofailSakib HossainZahid H MahmudAyse ErcumenJade Benjamin-Chung
Published in: medRxiv : the preprint server for health sciences (2024)
Using a randomised design in a large sample will allow us to minimize potential confounding by household wealth, which may have influenced prior observational studies' findings on concrete floors and health.Measurement of a diverse set of health outcomes within different domains (infections, antimicrobial resistance, child growth, cognitive development, mental health, quality of life) will capture broad potential benefits of the intervention.Longitudinal measurements will capture any variation in intervention impact as children learn to sit, crawl, walk and spend more time outdoors and their exposures change.Rich data on intermediate variables on household contamination and maternal bandwidth, time use, and mental health will allow us to investigate whether concrete floors influence child health and development primarily through environmental or maternal pathways.It is possible that child exposures outside the home will attenuate the effect of concrete floors on child health outcomes.
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