TIPS plus sequential systemic therapy of advanced HCC patients with tumour thrombus-related symptomatic portal hypertension.
Zhenkang QiuGuobao WangHuzheng YanHan QiMengxuan ZuoGuisong WangWeiwei JiangZixiong ChenJingbing XueLigong LuFujun ZhangFei GaoPublished in: European radiology (2022)
• Portal vein tumour thrombus (PVTT) is common in advanced hepatocellular carcinoma (HCC) and transforms compensated portal hypertension into symptomatic portal hypertension (SPH). • HCC patients with PVTT-related SPH have a very poor prognosis, and there are no effective treatments recommended by the guidelines. • Therefore, a treatment strategy that utilises a transjugular intrahepatic portosystemic shunt (TIPS) to manage SPH combined with sequential systemic therapy in advanced HCC patients is explored in this study for its feasibility and clinical value. This research can fill the gap in current research data to provide clinically meaningful treatment options.
Keyphrases
- poor prognosis
- blood pressure
- long non coding rna
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- peritoneal dialysis
- clinical practice
- patient reported outcomes
- electronic health record
- arterial hypertension
- bone marrow
- machine learning
- patient reported
- cell therapy