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Anal sphincter fatigability in assessing anal incontinence: A systematic review.

Dakshitha WickramasingheNilanka WickramasingheSohan Anjana KamburugamuwaDharmabandhu Nandadeva SamarasekeraJanindra WarusavitarneCarolynne Vaizey
Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2022)
Sphincter fatigability, measured by the Fatigability Rate Index, has good discriminating power for anal incontinence. A standardized protocol needs to be followed by future researchers. Graphical Abstract The analysis used six studies with 413 patients to compare Fatigue Rate Index between patients with AI and controls. All studies reported a lower FRI in patients with incontinence and the FRI was significantly lower in patients with AI (standardized mean difference [SMD] 1.636, p= 0.001). Conflicting results were reported on the correlation between FRI and AI symptom scores.
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