Melanin-concentrating hormone in rat nucleus accumbens or lateral hypothalamus differentially impacts morphine and food seeking behaviors.

Dong-Mei WangJianjun ZhangYunjing BaiXigeng ZhengMirmohammadali M AlizaminiWen ShangQingxiong YangMing LiYonghui LiNan Sui

Published in: Journal of psychopharmacology (Oxford, England) (2020)

These results suggest a clear double dissociation of melanin-concentrating hormone in morphine/food rewarding behaviors and melanin-concentrating hormone in the nucleus accumbens shell. Melanin-concentrating hormone could be a potential target for therapeutic intervention for morphine abuse without affecting natural rewards.

Keyphrases

randomized controlled trial
human health
mental health
climate change
electron transfer