Platelet and Leukocyte Mitochondrial Function With Cardiac Function and Self-Reported Health Status Among Obese Patients With Heart Failure.
Qiuhua ShenSamantha A CintronJanet D PiercePublished in: Nursing research (2024)
Platelet and leukocyte mitochondrial function was found to significantly correlate with some echocardiographic parameters and KCCQ scores. These findings provided preliminary data to support future research to further explore the potential of using platelets and leukocytes as surrogate biomarkers. Identifying easy-accessible mitochondrial biomarkers will be useful for assessing mitochondrial function to assist with early diagnosis and monitoring the effectiveness of mitochondrial-targeted therapy in HF patients.
Keyphrases
- ejection fraction
- oxidative stress
- peripheral blood
- end stage renal disease
- newly diagnosed
- randomized controlled trial
- systematic review
- adipose tissue
- type diabetes
- metabolic syndrome
- prognostic factors
- left ventricular
- weight loss
- mitral valve
- big data
- current status
- patient reported outcomes
- obese patients
- climate change