Investigating the correlation of the NF-κB and FoxP3 gene expression with the plasma levels of pro- and anti-inflammatory cytokines in rheumatoid arthritis patients.
Seyed Askar RoghaniRamin LotfiBijan SoleymaniZahra SamimiParisa FeizollahiShirin AsarZahra AbdanAli KhorasanizadehMahdi TaghadosiPublished in: Clinical rheumatology (2023)
In conclusion, classical NF-κB (P65/P50) and FoxP3 may have significant pro- and anti-inflammatory roles in RA pathogenesis, respectively. Key Point • NF-κB (P65/P50) has a contribution to the early phase of RA.
Keyphrases
- anti inflammatory
- rheumatoid arthritis patients
- signaling pathway
- disease activity
- lps induced
- gene expression
- regulatory t cells
- rheumatoid arthritis
- pi k akt
- nuclear factor
- oxidative stress
- systemic lupus erythematosus
- ankylosing spondylitis
- inflammatory response
- interstitial lung disease
- systemic sclerosis
- immune response
- cell proliferation