Targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest: a statistical analysis plan.

Janus Christian JakobsenJosef DankiewiczTheis LangeTobias CronbergGisela LiljaHelena LevinJan BělohlávekClifton CallawayAlain CariouDavid ErlingeJan HovdenesMichael JoannidisPer NordbergMauro OddoPaolo PelosiHans KirkegaardGlenn EastwoodChristian RylanderManoj SaxenaChristian StormFabio Silvio TacconeMatthew P WiseMatt P G MorganPaul YoungAlistair NicholHans FribergSusann UllénNiklas Nielsen

Published in: Trials (2020)

This SAP, which was prepared before completion of enrolment, should increase the validity of the TTM trial by mitigation of analysis-bias.

Keyphrases

cancer therapy
cardiac arrest
climate change

clinical trial
study protocol

brain injury
phase ii

randomized controlled trial
data analysis