High Fat Diet and High Cholesterol Diet Reduce Hepatic Vitamin D-25-Hydroxylase Expression and Serum 25-Hydroxyvitamin D3 Level through Elevating Circulating Cholesterol, Glucose, and Insulin Levels.
Tengfei ZhuJingyu ZhaoShu ZhuoZhimin HuShuyu Ouyangnull WunierShuting YuYan ChenYu LiYing-Ying LePublished in: Molecular nutrition & food research (2021)
These findings suggest that diet-induced elevation of circulating cholesterol, glucose, and insulin reduces serum 25(OH)D3 level through suppressing hepatic Cyp2r1 expression.