Ovarian environment aging: follicular fluid lipidomic and related metabolic pathways.

Fernanda Bertuccez CordeiroDaniela Antunes MontaniEduardo Jorge PilauFábio Cesar GozzoRenato FraiettaEdson Guimaraes Lo Turco

Published in: Journal of assisted reproduction and genetics (2018)

We suspect that aging may influence lipid metabolism in a downstream cascade leading, ultimately, to decreased oocyte quality. The discovery of target lipids may assist oocyte selection for IVF in the future. Furthermore, systems biology approach based on post-genomic medicine may help unravel a number of altered mechanisms not previously understood.

Keyphrases

small molecule
fatty acid
current status
high throughput
quality improvement
pregnant women
pregnancy outcomes
gene expression
single cell