Comparison of regional flortaucipir PET with quantitative tau immunohistochemistry in three subjects with Alzheimer's disease pathology: a clinicopathological study.
Michael J PontecorvoC Dirk KeeneThomas G BeachThomas J MontineAnupa K AroraMichael D DevousMichael NavitskyIan KennedyAbhinay D JoshiMing LuGeidy E SerranoLucia I SueAnthony J IntorciaShannon E RoseAngela WilsonLeanne HellsternNatalie ColemanMatthew FlitterPatricia AldeaAdam S FleisherMark A MintunAndrew SiderowfPublished in: EJNMMI research (2020)
The results of this pilot study support a quantitative relationship between cortical flortaucipir SUVr values and quantitative measures of Ptau at autopsy. Additional research including more cases is needed to confirm the generalizability of these results. Trial registration, NIH Clinicaltrials.gov NCT # 02516046. Registered August 27, 2015. https://clinicaltrials.gov/ct2/show/NCT02516046?term=02516046&draw=2&rank=1.