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Novel induction of broad-spectrum antibiotics by the human pathogen Legionella .

Carson J ShinTamara J O'Connor
Published in: mSphere (2024)
Natural products generated by microorganisms remain the most viable and abundant source of new antibiotics. However, their discovery depends on the ability to isolate and culture the producing organisms and to identify conditions that promote antibiotic production. Here, we identify a series of previously undescribed bacteria isolated from raw honey and specific culture conditions that induce the production of antimicrobial molecules that are active against a wide variety of pathogenic bacteria.
Keyphrases
  • endothelial cells
  • small molecule
  • staphylococcus aureus
  • high throughput
  • induced pluripotent stem cells
  • candida albicans
  • pluripotent stem cells
  • multidrug resistant