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The effect of mTOR activation and PTEN inhibition on human primordial follicle activation in ovarian tissue culture.

Zeinab GhezelayaghNaeimeh Sadat AbtahiMojtaba Rezazadeh ValojerdiBita Ebrahimi
Published in: Journal of assisted reproduction and genetics (2022)
Temporary in vitro treatment of human ovarian tissue with mTOR activators enhances the initiation of primordial follicle development and positively influences steroidogenesis after short-term culture.
Keyphrases
  • endothelial cells
  • cell proliferation
  • induced pluripotent stem cells
  • pluripotent stem cells