Comparing paediatric- and adult-onset linear morphoea in a large tertiary-referral scleroderma centre.
Amanda M SaracinoChristina GeorgeSvetlana I NihtyanovaChristopher P DentonPublished in: Journal of scleroderma and related disorders (2020)
Linear morphoea in adults can be a severe disease with extracutaneous, autoimmune and systemic features. Adults with paediatric-onset disease appear to have more severe cumulative damage, greater functional impairment and ongoing disease activity. This patient subgroup may require particularly close monitoring and more aggressive therapy.
Keyphrases
- disease activity
- rheumatoid arthritis
- systemic lupus erythematosus
- intensive care unit
- emergency department
- rheumatoid arthritis patients
- ankylosing spondylitis
- early onset
- drug induced
- systemic sclerosis
- multiple sclerosis
- oxidative stress
- case report
- interstitial lung disease
- stem cells
- idiopathic pulmonary fibrosis