A blockage monoclonal antibody protocol as an alternative strategy to avoid anti-CD38 interference in immunohematological testing.
Karen N Chinoca ZizaTainá A PaivaSabrina R MotaMarcia Regina DezanLuciana Cayres SchmidtDenise Menezes BrunettaGustavo RicciFernando Valadares BasquesFernando Barroso-DuarteVanderson RochaAlfredo Mendrone-JuniorCarla Luana DinardoPublished in: Transfusion (2019)
This study validated a new strategy to minimize the interference of DARA on immunohematological tests. The protocol preserves the integrity of RBC antigens, permitting the detection of antibodies from all blood group systems. The BMAP has potential use in other situations where specific antibodies may interfere with pretransfusion screening.