CeO 2 Nanoparticles to Promote Wound Healing: A Systematic Review.

Cerium (Ce) is recognized as one of rare-earth elements that has become a hot topic in the field of materials research due to its electronic layer structure, and unique antioxidant abilities of its oxide (CeO 2 ). Cerium oxide nanoparticles (CeO 2 NPs) have demonstrated their potential as an antioxidant and antibacterial agent. Current researches focused on whether they can be used to promote wound healing and in what manner. This article provides a systematic review of the various forms of CeO 2 NPs that have been used in wound-healing materials over the past decade, as well as the effectiveness demonstrated by in vivo and in vitro experiments, with a focus on the relationship between concentration and effectiveness. CeO 2 NPs are expected to become effective ingredients in dressings that require antibacterial, antioxidant, and wound healing promoting properties. This article serves as a reference for further research and clinical applications of nano-sized CeO 2 in wound healing. This article is protected by copyright. All rights reserved.