Determining the Effectiveness of Fibrin Sealants in Reducing Complications in Patients Undergoing Lateral Neck Dissection (DEFeND): A Randomised External Pilot Trial.
Mandeep S BajwaRichard JacksonJagtar DhandaCatrin Tudur SmithRichard J ShawAndrew Graeme SchachePublished in: Cancers (2023)
The proposed trial design was effective, and a definitive surgical trial is feasible. Whilst there was a tendency for FS to improve clinical outcomes, the effect size did not reach clinical or statistical significance. (ISRCTN99181100).