Influenza A (H1N1) virus induced long-term remission in a refractory acute myeloid leukaemia.

You et al. present an extraordinary case of a refractory acute myeloid leukaemia (AML) patient who achieved long-term complete remission after infection with Influenza A. Using mouse models, the researchers examined the underlying immunological mechanisms and discovered a decrease in leukaemia proliferation and improved survival in Influenza-A virus-infected mice. These results indicate the potential therapeutic relevance of Influenza A in the treatment of haematological cancers. Commentary on: You et al. Influenza A (H1N1) virus induced long-term remission in a refractory acute myeloid leukemia. Br J Haematol 2023 (Online ahead of print). doi: 10.1111/bjh.18876.