Jan-Henning Klusmann (J H Klusmann)

Scopus Author ID ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2013-2024
Publications (10 Years): 29

Top Venues

Blood

Leukemia

Pediatric blood & cancer

Nature communications

Martin Luther University Halle-Wittenberg

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Martin Luther University Halle-Wittenberg Jan 01 2018

Germany

Professor :: Pediatrics and Pediatric Hematology/Oncology

Universitätsklinikum Halle Jan 01 2018

Germany

Director :: Pediatrics I

Medizinische Hochschule Hannover Feb 01 2016 - Dec 31 2017

Germany

Senior physician (consultant) :: Pediatric Hematology and Oncology

Medizinische Hochschule Hannover - Dec 31 2017

Germany

Emmy Noether Junior Research Group leader :: Pediatric Hematology and Oncology

Medizinische Hochschule Hannover - Dec 01 2017

Germany

Head of Diagnostics in Pediatric Hematology :: Pediatric Hematology and Oncology

Medizinische Hochschule Hannover Jan 08 2014 - Jan 31 2016

Germany

Fellow :: Pediatric Hematology and Oncology

Medizinische Hochschule Hannover

Germany

Resident :: Pediatrics

Medizinische Hochschule Hannover Jul 01 2007

Germany

Research Fellow :: Pediatric Hematology and Oncology

Children's Hospital Boston

United States

Research Fellow :: Pediatric Hematology and Oncology (Laboratory of Stuart H. Orkin, M.D.)

Children's Hospital Boston

United States

Doctoral student :: Pediatric Hematology and Oncology (Laboratory of Stuart H. Orkin, M.D.)

Publications

Milica Miladinovic, Dirk Reinhardt, Henrik Hasle, Bianca F Goemans, Masanori Yoshida, Johann K Hitzler, Jan-Henning Klusmann
Guideline for treating relapsed or refractory myeloid leukemia in children with Down syndrome. Pediatric blood & cancer (2024)
Milica Miladinovic, Dirk Reinhardt, Henrik Hasle, Bianca F Goemans, Masanori Yoshida, Johann K Hitzler, Jan-Henning Klusmann
Guideline for treating relapsed or refractory myeloid leukemia in children with Down syndrome. Pediatric blood & cancer 71 (9) (2024)
Milica Miladinovic, Dirk Reinhardt, Henrik Hasle, Bianca F Goemans, Masanori Yoshida, Johann K Hitzler, Jan-Henning Klusmann
Guideline for treating relapsed or refractory myeloid leukemia in children with Down syndrome. Pediatric blood & cancer 71 (9) (2024)
Jan-Henning Klusmann
MYC-stery of Down syndrome unraveled. Blood 143 (25) (2024)
Islam Alshamleh, Nina Kurrle, Philipp Makowka, Raj Bhayadia, Rahul Kumar, Sebastian Süsser, Marcel Seibert, Damian Ludig, Sebastian Wolf, Sebastian E Koschade, Karoline Stoschek, Johanna Kreitz, Dominik C Fuhrmann, Rosa Toenges, Marco Notaro, Federico Comoglio, Jan Jacob Schuringa, Tobias Berg, Bernhard Brüne, Daniela S Krause, Jan-Henning Klusmann, Thomas Oellerich, Frank Schnuetgen, Harald Schwalbe, Hubert Serve
PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia. Leukemia (2023)
Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Enikő Regényi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia. Blood 141 (10) (2023)
Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Enikő Regényi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia. Blood 141 (10) (2023)
Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Enikő Regényi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia. Blood 141 (10) (2023)
Milica Miladinovic, Jan-Henning Klusmann
Influenza A (H1N1) virus induced long-term remission in a refractory acute myeloid leukaemia. British journal of haematology (2023)
Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Enikő Regényi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia. Blood 141 (10) (2023)
Hannah J Uckelmann, Jan-Henning Klusmann
Double trouble: IRAK1/4 inhibitors in AML/MDS. Blood 142 (11) (2023)
Hasan Issa, Raj Bhayadia, Robert Winkler, Laura Elise Swart, Dirk Heckl, Jan-Henning Klusmann
Preclinical testing of miRNA-193b-3p mimic in acute myeloid leukemias. Leukemia (2023)
Andrea Jarisch, Emilia Salzmann-Manrique, Jan Soerensen, Gudrun Sach, Eva Rettinger, Andre Willasch, Shahrzad Bakhtiar, Dieter Klarmann, Susanne Bräuninger, Laura M Moser, Julia Fekadu, Martin Hutter, Thomas Klingebiel, Jan-Henning Klusmann, Peter Bader, Halvard Bonig
Donor-type red blood cell transfusion to deplete isoagglutinins prior to allogeneic stem cell transplantation from ABO major incompatible bone marrow donors. British journal of haematology (2023)
Danxiu Li, Xin Wang, Hui Miao, Hao Liu, Maogui Pang, Hao Guo, Minghui Ge, Sarah E Glass, Stephan Emmrich, Songtao Ji, Yun Zhou, Xiaoni Ye, Huajie Mao, Jing Wang, Qi Liu, Taewan Kim, Jan-Henning Klusmann, Cunxi Li, Zhenxiong Liu, Haifeng Jin, Yongzhan Nie, Kaichun Wu, Daiming Fan, Xu Song, Xin Wang, Ling Li, Yuanyuan Lu, Xiao-Di Zhao
The lncRNA MIR99AHG directs alternative splicing of SMARCA1 by PTBP1 to enable invadopodia formation in colorectal cancer cells. Science signaling 16 (803) (2023)
Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Eniko Melinda Regenyi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
RUNX1 isoform disequilibrium promotes the development of trisomy 21 associated myeloid leukemia. Blood (2022)
Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Eniko Melinda Regenyi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
RUNX1 isoform disequilibrium promotes the development of trisomy 21 associated myeloid leukemia. Blood (2022)
Juliane Grimm, Raj Bhayadia, Lucie Gack, Dirk Heckl, Jan-Henning Klusmann
Combining LSD1 and JAK-STAT inhibition targets Down syndrome-associated myeloid leukemia at its core. Leukemia 36 (7) (2022)
Cornelis M van Tilburg, Elke Pfaff, Kristian W Pajtler, Karin P S Langenberg, Petra Fiesel, Barbara C Jones, Gnana Prakash Balasubramanian, Sebastian Stark, Pascal D Johann, Mirjam Blattner-Johnson, Kathrin Schramm, Nicola Dikow, Steffen Hirsch, Christian Sutter, Kerstin Grund, Arend von Stackelberg, Andreas E Kulozik, Andrej Lissat, Arndt Borkhardt, Richard P Meisel, Dirk Reinhardt, Jan-Henning Klusmann, Gudrun Fleischhack, Stephan Tippelt, Dietrich von Schweinitz, Irene Schmid, Christof Maria Kramm, Andre O von Bueren, Gabriele Calaminus, Peter Vorwerk, Norbert Graf, Frank Westermann, Matthias Fischer, Angelika Eggert, Birgit Burkhardt, Wilhelm Wößmann, Michaela Nathrath, Stefanie Hecker-Nolting, Michael C Frühwald, Dominik T Schneider, Ines B Brecht, Petra Ketteler, Simone Fulda, Ewa Koscielniak, Michael T Meister, Monika Scheer, Simone Hettmer, Matthias Schwab, Roman Tremmel, Ingrid Öra, Caroline Hutter, Nicolas U Gerber, Olli Lohi, Bernarda Kazanowska, Antonios Kattamis, Maria Filippidou, Bianca Frederika Goemans, C Michel Zwaan, Till Milde, Natalie Jäger, Stephan Wolf, David Reuss, Felix Sahm, Andreas von Deimling, Uta Dirksen, Angelika Freitag, Peter Lichter, David T W Jones, Jan J Molenaar, David Capper, Stefan M Pfister
The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets. Cancer discovery 11 (11) (2021)
Oriol Alejo-Valle, Karoline Weigert, Raj Bhayadia, Michelle Ng, Hasan Issa, Christoph Beyer, Stephan Emmrich, Konstantin Schuschel, Christian Ihling, Andrea Sinz, Martin Zimmermann, Claudia Wickenhauser, Marius Flasinski, Eniko Melinda Regenyi, Maurice Labuhn, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis. Blood (2021)
Sina Al-Kershi, Richard Golnik, Marius Flasinski, Katharina Waack, Mareike Rasche, Ursula Creutzig, Michael Dworzak, Dirk Reinhardt, Jan-Henning Klusmann
Recommendations for Diagnosis and Treatment of Children with Transient Abnormal Myelopoiesis (TAM) and Myeloid Leukemia in Down Syndrome (ML-DS). Klinische Padiatrie 233 (6) (2021)
Julius Lukes, Petr Danek, Oriol Alejo-Valle, Eliska Potuckova, Ondřej Gahura, Dirk Heckl, Julia Starkova, Jan Stary, Ester Mejstrikova, Meritxell Alberich-Jorda, Jan Zuna, Jan Trka, Jan-Henning Klusmann, Marketa Zaliova
Chromosome 21 gain is dispensable for transient myeloproliferative disorder driven by a novel GATA1 mutation. Leukemia 34 (9) (2020)
Konstantin Schuschel, Matthias Helwig, Stefan Hüttelmaier, Dirk Heckl, Jan-Henning Klusmann, Jessica I Hoell
RNA-Binding Proteins in Acute Leukemias. International journal of molecular sciences 21 (10) (2020)
Andreas Kloetgen, Sujitha Duggimpudi, Konstantin Schuschel, Kebria Hezaveh, Daniel Picard, Heiner Schaal, Marc Remke, Jan-Henning Klusmann, Arndt Borkhardt, Alice C McHardy, Jessica I Hoell
YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA. International journal of molecular sciences 21 (12) (2020)
Marius Flasinski, Kira Scheibke, Martin Zimmermann, Ursula Creutzig, Katarina Reinhardt, Femke Verwer, Valerie de Haas, Vincent H J van der Velden, Christine von Neuhoff, C Michel Zwaan, Dirk Reinhardt, Jan-Henning Klusmann
Low-dose cytarabine to prevent myeloid leukemia in children with Down syndrome: TMD Prevention 2007 study. Blood advances 2 (13) (2019)
Mareike Rasche, Martin Zimmermann, Lisa Borschel, Jean-Pierre Bourquin, Michael Dworzak, Thomas Klingebiel, Thomas Lehrnbecher, Ursula Creutzig, Jan-Henning Klusmann, Dirk Reinhardt
Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012. Leukemia 32 (10) (2018)
Madita Uffmann, Mareike Rasche, Martin Zimmermann, Christine von Neuhoff, Ursula Creutzig, Michael Dworzak, Lenie Scheffers, Henrik Hasle, C Michel Zwaan, Dirk Reinhardt, Jan-Henning Klusmann
Therapy reduction in patients with Down syndrome and myeloid leukemia: the international ML-DS 2006 trial. Blood 129 (25) (2017)
Erik Pittermann, Nico Lachmann, Glenn MacLean, Stephan Emmrich, Mania Ackermann, Gudrun Göhring, Brigitte Schlegelberger, Karl Welte, Axel Schambach, Dirk Heckl, Stuart H Orkin, Tobias Cantz, Jan-Henning Klusmann
Gene correction of HAX1 reversed Kostmann disease phenotype in patient-specific induced pluripotent stem cells. Blood advances 1 (14) (2017)
Adrian Schwarzer, Stephan Emmrich, Franziska Schmidt, Dominik Beck, Michelle Ng, Christina Reimer, Felix Ferdinand Adams, Sarah Grasedieck, Damian Witte, Sebastian Käbler, Jason Wing Hon Wong, Anushi Shah, Yizhou Huang, Razan Jammal, Aliaksandra Maroz, Mojca Jongen-Lavrencic, Axel Schambach, Florian Kuchenbauer, John E Pimanda, Dirk Reinhardt, Dirk Heckl, Jan-Henning Klusmann
The non-coding RNA landscape of human hematopoiesis and leukemia. Nature communications 8 (1) (2017)
Dakai Yang, Qinggong Yuan, Asha Balakrishnan, Heike Bantel, Jan-Henning Klusmann, Michael P Manns, Michael Ott, Tobias Cantz, Amar Deep Sharma
MicroRNA-125b-5p mimic inhibits acute liver failure. Nature communications 7 (2016)
S Emmrich, J E Katsman-Kuipers, K Henke, M E Khatib, R Jammal, F Engeland, F Dasci, C M Zwaan, M L den Boer, L Verboon, J Stary, A Baruchel, V de Haas, A A Danen-van Oorschot, M Fornerod, R Pieters, D Reinhardt, Jan-Henning Klusmann, M M van den Heuvel-Eibrink
miR-9 is a tumor suppressor in pediatric AML with t(8;21). Leukemia 28 (5) (2013)
M V Stankov, M El Khatib, B Kumar Thakur, K Heitmann, D Panayotova-Dimitrova, J Schoening, J P Bourquin, N Schweitzer, M Leverkus, K Welte, D Reinhardt, Z Li, S H Orkin, G M N Behrens, Jan-Henning Klusmann
Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy. Leukemia 28 (3) (2013)

Jan-Henning Klusmann.css-eqlu8i{font-size:small;padding-left:4px;} (J H Klusmann)

Publication Activity (10 Years)

Top Topics

Top Venues

Jan-Henning Klusmann (J H Klusmann)