Preoperative Assessment of Medication-Related Osteonecrosis of the Jaw Using [18F]fluoride Positron Emission Tomography (PET)/CT and [18F]fluorodeoxyglucose PET/MRI in Correlation with Histomorphometry and Micro-CT-A Prospective Comparative Study.
Christian Philipp ReinertChristina PfannenbergBrigitte GückelHelmut DittmannChristian Peter la FougèreKonstantin NikolaouSiegmar ReinertRouven SchönhofSebastian HoefertPublished in: Diagnostics (Basel, Switzerland) (2024)
In summary, [18F]fluoride PET accurately identified MRONJ extent, revealing functional changes in jawbone remodeling not visible on CT. [18F]FDG PET showed differences in bone and soft tissue, though less pronounced. This method aids in evaluating disease activity and guiding treatment planning, requiring further research for optimal surgical approaches based on tracer uptake.
Keyphrases
- positron emission tomography
- pet ct
- computed tomography
- disease activity
- soft tissue
- rheumatoid arthritis
- systemic lupus erythematosus
- contrast enhanced
- pet imaging
- rheumatoid arthritis patients
- magnetic resonance imaging
- ankylosing spondylitis
- drinking water
- dual energy
- image quality
- juvenile idiopathic arthritis
- healthcare
- bone mineral density
- patients undergoing
- antiretroviral therapy
- emergency department
- postmenopausal women
- body composition
- adverse drug