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Dexamethasone downregulates SIRT1 and IL6 and upregulates EDN1 genes in stem cells derived from gingivae via the AGE/RAGE pathway.

Hyunjin LeeMinji KimYun-Hee ParkJun-Beom Park
Published in: Biotechnology letters (2018)
Application of dexamethasone reduced the expression of SIRT1 and IL6 but enhanced the expression of EDN1 of stem cells.
Keyphrases
  • stem cells
  • poor prognosis
  • low dose
  • high dose
  • oxidative stress
  • ischemia reperfusion injury
  • binding protein
  • cell therapy
  • genome wide
  • long non coding rna
  • transcription factor