Probiotics and the Microbiota-Gut-Brain Axis: Focus on Psychiatry.
Sabrina MorklMary I ButlerAnna HollJohn F CryanTimothy G DinanPublished in: Current nutrition reports (2021)
Probiotics are likely to improve depression but not schizophrenia. Regarding anxiety, there is only one trial which showed an effect of a multispecies probiotic. However, determinants like the duration of treatment, dosage and interactions have not been thoroughly investigated and deserve more scientific attention. Microbiome-based therapies such as probiotics could be cautiously recommended for depression to enhance beneficial bacteria in the gut and to improve mood through the gut-brain axis.
Keyphrases
- sleep quality
- bipolar disorder
- depressive symptoms
- resting state
- white matter
- functional connectivity
- clinical trial
- cerebral ischemia
- study protocol
- working memory
- phase iii
- randomized controlled trial
- multiple sclerosis
- phase ii
- atomic force microscopy
- mass spectrometry
- subarachnoid hemorrhage
- brain injury
- blood brain barrier
- bacillus subtilis
- smoking cessation
- replacement therapy
- high speed