Management of severe aortic stenosis in asymptomatic patients in the new AVATAR.
Pradeep NarayanPublished in: Indian journal of thoracic and cardiovascular surgery (2022)
Management of asymptomatic patients with severe aortic stenosis remains debatable. Until now, evidence on the subject was limited to observational studies, registry data, and meta-analyses. Aortic Valve Replacement Versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis trial thus is the first randomized controlled trial assessing the role of surgery in asymptomatic patients with severe aortic stenosis. A critical evaluation of the study along with discussion on existing evidence has been provided in this appraisal.
Keyphrases
- aortic stenosis
- ejection fraction
- aortic valve replacement
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- aortic valve
- left ventricular
- randomized controlled trial
- early onset
- coronary artery disease
- systematic review
- end stage renal disease
- meta analyses
- chronic kidney disease
- minimally invasive
- heart failure
- electronic health record
- phase iii
- patient reported outcomes
- artificial intelligence
- percutaneous coronary intervention