Quantifying the net expression of metabolites allows for the identification of cells with metabolic pathways that result in increased biomolecule production, which is essential for improving the yield and reducing the cost of industrial biomanufacturing. Technological advancements in vibrational microscopy instrumentation will greatly benefit biofoundries as a complementary approach for non-destructive cell screening.
Keyphrases
- single cell
- high resolution
- ms ms
- cell therapy
- induced apoptosis
- poor prognosis
- molecular dynamics simulations
- density functional theory
- heavy metals
- high throughput
- stem cells
- cell cycle arrest
- wastewater treatment
- single molecule
- oxidative stress
- risk assessment
- optical coherence tomography
- mesenchymal stem cells
- bone marrow