Dual role for microbial short-chain fatty acids in modifying SIV disease trajectory following anti-α4β7 antibody administration.

Samuel D JohnsonNageswara PilliJianshi YuLindsey A KnightMaureen A Kane Siddappa N Byrareddy

Published in: Annals of medicine (2024)

Taken together, these data demonstrate the therapeutic advantages of anti-α4β7 antibody administration during HIV/SIV infection and that the efficacy of anti-α4β7 antibody may depend on microbiome composition and SCFA generation.

Keyphrases

fatty acid
antiretroviral therapy
hiv infected
hiv positive
human immunodeficiency virus
hepatitis c virus
hiv aids
electronic health record
machine learning
south africa
deep learning
artificial intelligence
data analysis
men who have sex with men