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Salivary Gland Toxicity of PSMA-Targeted Radioligand Therapy with 177 Lu-PSMA and Combined 225 Ac- and 177 Lu-Labeled PSMA Ligands (TANDEM-PRLT) in Advanced Prostate Cancer: A Single-Center Systematic Investigation.

Thomas LangbeinHarshad R KulkarniChristiane SchuchardtDirk MuellerGerd Fabian VolkRichard P Baum
Published in: Diagnostics (Basel, Switzerland) (2022)
Lu-PSMA-I&T/-617 causes only minor SG toxicity, while one cycle of Tandem-PRLT results in a significant SG impairment. This standardized protocol may help to objectify and quantify SG dysfunction.
Keyphrases
  • pet ct
  • pet imaging
  • prostate cancer
  • oxidative stress
  • randomized controlled trial
  • radical prostatectomy
  • stem cells
  • computed tomography
  • cancer therapy
  • mesenchymal stem cells
  • replacement therapy