Relative impact of lymph-node metastasis and seminal vesical invasion on oncologic outcomes following radical prostatectomy.
Rodrigo Rodrigues PessoaReza NabavizadehParas ShahIgor FrankMathew TollefsonVidit SharmaLaureano J RangelJohn C ChevilleR Jeffrey KarnesStephen A BoorjianPublished in: Prostate cancer and prostatic diseases (2023)
SVI represents an adverse pathologic feature such that the presence of a single positive pelvic lymph node did not further adversely impact prognosis. Meanwhile, a significant number of involved nodes was associated with decreased survival. These findings may aid in risk-stratification as well as clinical trial design for such high-risk patients following surgery.
Keyphrases
- radical prostatectomy
- lymph node metastasis
- prostate cancer
- lymph node
- clinical trial
- end stage renal disease
- neoadjuvant chemotherapy
- ejection fraction
- rectal cancer
- minimally invasive
- squamous cell carcinoma
- newly diagnosed
- chronic kidney disease
- sentinel lymph node
- prognostic factors
- machine learning
- peritoneal dialysis
- papillary thyroid
- emergency department
- locally advanced
- deep learning
- randomized controlled trial
- cell migration
- open label
- robot assisted
- free survival