The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity.

Yujia LiMax Xuezhong MaBo QinLiang-Tzung LinChristopher D RichardsonJordan J Feld Ian D McGilvray Limin Chen

Published in: Mediators of inflammation (2019)

USP18 stimulates HCV production and blunts the effect of both type I and III IFNs by fostering a cellular environment characterized by upregulation of CD81, promoting virus entry and infectivity.

Keyphrases

hepatitis c virus
human immunodeficiency virus
cell proliferation
small molecule
poor prognosis
nk cells
long non coding rna