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Psychotropic drug concentrations and clinical outcomes in children and adolescents: a systematic review.

Sanne Maartje KloosterboerDenise VierhoutJana StojanovaKarin Maria EgbertsManfred GerlachGwen C DielemanManon H J HillegersKimberly M PasseTeun van GelderBram DierckxBirgit C P Koch
Published in: Expert opinion on drug safety (2020)
In order to better support routine TDM in child- and adolescent psychiatry, future work must improve in aspects of study design, execution and reporting to demonstrate drug concentration-effect relationships. The quality criteria proposed in this work can guide future TDM research. Systematic review protocol and registration PROSPERO CRD42018084159.
Keyphrases
  • systematic review
  • adverse drug
  • current status
  • mental health
  • meta analyses
  • young adults
  • randomized controlled trial
  • clinical practice
  • drug induced
  • emergency department
  • quality improvement