Sex-differences in circulating biomarkers during acute myocardial infarction: An analysis from the SWEDEHEART registry.
Kai M EggersLars LindhagenTomasz BaronDavid ErlingeMarcus HjortTomas JernbergNina JohnstonGyörgy Marko-VargaMelinda RezeliJonas SpaakBertil LindahlPublished in: PloS one (2021)
Severable sex-differences exist in the expression of biomarkers in patients with myocardial infarction. While these differences had no impact on outcome, our data suggest the presence of various sex-related pathways involved in the development of coronary atherosclerosis, the progression to plaque rupture and acute myocardial damage, with a greater heterogeneity in women.
Keyphrases
- acute respiratory distress syndrome
- acute myocardial infarction
- left ventricular
- coronary artery disease
- poor prognosis
- liver failure
- polycystic ovary syndrome
- heart failure
- coronary artery
- percutaneous coronary intervention
- respiratory failure
- cardiovascular disease
- oxidative stress
- aortic stenosis
- electronic health record
- drug induced
- single cell
- binding protein
- pregnancy outcomes
- aortic dissection
- type diabetes
- machine learning
- intensive care unit
- acute coronary syndrome
- insulin resistance
- pregnant women
- aortic valve
- deep learning