Potential of Direct Oral Anticoagulant in Bleeding After Gastric Endoscopic Submucosal Dissection: A Systematic Review and Meta-Analysis.

Kazutoshi HiguchiOsamu GotoAkihisa MatsudaShun NakagomeTsugumi HabuYumiko IshikawaEriko KoizumiKumiko KiritaHiroto NodaTakeshi OndaTeppei AkimotoJun OmoriNaohiko AkimotoHiroshi YoshidaKatsuhiko Iwakiri

Published in: Digestive diseases and sciences (2024)

This meta-analysis reveals that the bleeding risk of DOACs is higher than that of non-antithrombotics and antiplatelets, whereas it is comparable to that of warfarin. Gastric ESD in patients on anticoagulants requires careful postoperative management.

Keyphrases

atrial fibrillation
endoscopic submucosal dissection
systematic review
end stage renal disease
direct oral anticoagulants
venous thromboembolism
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
randomized controlled trial
patient reported outcomes
meta analyses
case control