Irsogladine maleate alters expression of a tight junction protein in portal hypertensive gastropathy.
Keiji YokoyamaMakoto IrieNaoaki TsuchiyaEri YamauchiMotoko KawashimaTakashi MiyayamaHiromi FukudaRyo YamauchiKaoru UmedaKazuhide TakataTakashi TanakaShinjiro InomataDaisuke MoriharaYasuaki TakeyamaSatoshi ShakadoShotaro SakisakaFumihito HiraiPublished in: Journal of gastroenterology and hepatology (2020)
The present pilot study suggested that IM might improve the gastric mucosa in PHG through restoration of TJ-protein claudin-3.