Response to random apheresis platelets versus HLA-selected platelets versus pooled platelets in HLA-sensitized patients.

Chakri GavvaJeffrey BarrosoTerry GernsheimerRyan A MetcalfPaul WarnerMonica B Pagano

Published in: Transfusion (2019)

HLA-selected PLTs resulted in higher mean CCIs and more successful transfusions. There was no significant difference in mean CCI or success rate when transfusing RAPs versus PPs to HLA-sensitized patients. Future studies should assess clinical outcomes in HLA-sensitized patients receiving each type of PLT product.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
randomized controlled trial
clinical trial
neuropathic pain
study protocol
current status
open label