Simulations of sequence evolution: how (un)realistic they are and why.

All simulated and empirical MSAs, as well as all analysis results, are available at https://cme.h-its.org/exelixis/material/simulation_study.tar.gz. All scripts required to reproduce our results are available at https://github.com/tschuelia/SimulationStudy and https://github.com/JohannaTrost/seqsharp.