Meta-analysis of the cumulative risk of endometrial malignancy and systematic review of endometrial surveillance in extended tamoxifen therapy.

Christina A Fleming Helen M HeneghanD O'BrienD P McCartanE W McDermottR S Prichard

Published in: The British journal of surgery (2018)

Extended adjuvant tamoxifen is associated with an increase in endometrial cancer. No clear benefit has been shown for routine endometrial surveillance in asymptomatic patients on tamoxifen therapy.

Keyphrases

endometrial cancer
systematic review
meta analyses
breast cancer cells
end stage renal disease
estrogen receptor
public health
positive breast cancer
newly diagnosed
chronic kidney disease
ejection fraction
prognostic factors
randomized controlled trial
stem cells
mesenchymal stem cells
cell therapy
case control