Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training.
Michael D RobertsMatthew A RomeroChristopher B MobleyPetey W MumfordPaul A RobersonCody T HaunChristopher G VannShelby C OsburnHudson H HolmesRory A GreerChristopher M LockwoodHailey A ParryAndreas N KavazisPublished in: PeerJ (2018)
Our data suggest myofibrillar or sarcoplasmic protein concentrations do not differ between HI versus LO anabolic responders prior to or following a 12-week RET program. Greater mitochondrial volume in HI responders may have facilitated greater anabolism, and myofibril myozenin-1 protein levels may represent a biomarker that differentiates anabolic responses to RET. However, mechanistic research validating these hypotheses is needed.