Colonic Epithelial Angiotensin-Converting Enzyme 2 (ACE2) Expression in Blacks and Whites: Potential Implications for Pathogenesis Covid-19 Racial Disparities.
Mart De La CruzDavid P NunesVaishali BhardwajDeepika SubramanyanCaroline ZaworskiPriya RoyHemant K RoyPublished in: Journal of racial and ethnic health disparities (2021)
To our knowledge, this is the first report on racial differences inACE2 and TMPRSS2 mucosal expression. This may provide potential biological underpinnings for the disproportionately higher mortality of Covid-19 in Blacks and should spur future studies.