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Longitudinal Analysis of Inflammatory Response to SARS-CoV-2 in the Upper Respiratory Tract Reveals an Association with Viral Load, Independent of Symptoms.

Diem-Lan VuPaola Martinez-MurilloFiona PignyMaria VonoBenjamin MeyerChristiane S EberhardtSylvain LemeilleElodie Von DachGéraldine Blanchard-RohnerIsabella EckerleAngela HuttnerClaire-Anne SiegristLaurent KaiserArnaud M Didierlaurent
Published in: Journal of clinical immunology (2021)
The nasal epithelium is an active site of cytokine response against SARS-CoV-2 that can last more than 2 weeks; in this mild COVID-19 cohort, anosmia was not associated with increases in any locally produced cytokines.
Keyphrases
  • sars cov
  • respiratory tract
  • inflammatory response
  • respiratory syndrome coronavirus
  • lipopolysaccharide induced
  • lps induced
  • cross sectional
  • sleep quality
  • immune response
  • depressive symptoms