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Current progress in CRISPR-based diagnostic platforms.

Khushal KhambhatiGargi BhattacharjeeVijai Singh
Published in: Journal of cellular biochemistry (2018)
The CRISPR-Cas system is a key technology for genome editing and regulation in a wide range of organisms and cell types. Recently, CRISPR-Cas-based diagnostic platform has shown idealistic properties for pathogen detection. Integrating the CRISPR-Cas platform along with lateral flow system allows rapid, sensitive, specific, cheap, and reliable diagnostic. It has the potential to be in frontline for not only pathogen detection during the epidemic outbreak, but also cancer, and genetic diseases.
Keyphrases
  • crispr cas
  • genome editing
  • loop mediated isothermal amplification
  • high throughput
  • label free
  • candida albicans
  • single cell
  • genome wide
  • papillary thyroid
  • stem cells
  • risk assessment
  • human health
  • gram negative