Protein profiling of extracellular vesicles from iPSC-derived astrocytes of patients with ALS/PDC in Kii peninsula.

Hiroya Kobayashi Koji Ueda Yasumasa Kokubo Mitsuru Ishikawa Nicolas Leventoux Ryogen Sasaki Yoshifumi Hirokawa Yasumasa Kokubo Hideyuki Okano

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2023)

Proteins contained in EVs from astrocytes unveil protective support to neurons and may reflect the molecular pathomechanism of Kii ALS/PDC; accordingly, they may be potential biomarker candidates of Kii ALS/PDC.

Keyphrases

amyotrophic lateral sclerosis
single cell
protein protein