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An Efficient Combination of Convolutional Neural Network and LightGBM Algorithm for Lung Cancer Histopathology Classification.

Esraa A-R HamedMohammed A-M SalemNagwa L BadrMohamed F Tolba
Published in: Diagnostics (Basel, Switzerland) (2023)
The most dangerous disease in recent decades is lung cancer. The most accurate method of cancer diagnosis, according to research, is through the use of histopathological images that are acquired by a biopsy. Deep learning techniques have achieved success in bioinformatics, particularly medical imaging. In this paper, we present an innovative method for rapidly identifying and classifying histopathology images of lung tissues by combining a newly proposed Convolutional Neural Networks (CNN) model with a few total parameters and the enhanced Light Gradient Boosting Model (LightGBM) classifier. After the images have been pre-processed in this study, the proposed CNN technique is provided for feature extraction. Then, the LightGBM model with multiple threads has been used for lung tissue classification. The simulation result, applied to the LC25000 dataset, demonstrated that the novel technique successfully classifies lung tissue with 99.6% accuracy and sensitivity. Furthermore, the proposed CNN model has achieved the lowest training parameters of only one million parameters, and it has also achieved the shortest processing time of just one second throughout the feature extraction process. When this result is compared with the most recent state-of-the-art approaches, the suggested approach has increased effectiveness in the areas of both disease classification accuracy and processing time.
Keyphrases
  • convolutional neural network
  • deep learning
  • artificial intelligence
  • machine learning
  • healthcare
  • high resolution
  • randomized controlled trial
  • systematic review
  • young adults
  • tandem mass spectrometry